Dr Temple Grandin Thinking In Pictures

Dr Temple Grandin Thinking In Pictures

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Dr Temple Grandin Thinking In Pictures

What is Stem Cell Therapy?

Everybody is Born distinct , some are born perfectly healthy and remain healthy for the remainder of their lives, some are born with certain neuromuscular disorders, even though some may develop degenerative disorders. Stem Cell Therapy (SCT) is the treatment of various disorders, non-serious to life threatening, using stem cells. |} These stem cells can be procured from a lot of different sources and used to potentially treat over 80 ailments , such as neuromuscular and degenerative disorders.

Hematopoietic Ailments (eg leukaemia, thallassemia, aplastic anemia, MDS, sickle cell anemia, storage disorders etc.) affect the bone marrow and manifest with different systemic complications. |} Stem cells from a donor (either from cord blood or bone marrow) are known to reconstitute the bone marrow and permanently overcome the disorder. |}

Degenerative Disorders arise in degeneration or wear and tear of bone, cartilage, muscle, fat or any other tissue, cell or organ. This could occur due to a variety of reasons, but it's normally the procedure called aging, or'getting old' that is the biggest cause. The disorders have a slow and insidious onset but once contracted, can be life threatening, pain-staking and lifelong. These disorders can affect almost any organ of the body. {The common degenerative disorders are diabetes, osteoarthritis, stroke, and chronic renal failure, congestive cardiac failure, myocardial infarction, Alzheimer's disease, Parkinson's disease etc.. |}

Stem cells in Unconventional sources

Currently, Traditional treatment for many of these disorders are not very powerful, but stem cell treatment was showing a lot of promising consequences all over the world. This is possible due to this amazing and special features of stem cells. The therapy is secure, speedy and often completed within a day or two. Still, the results are far better than the long and ineffective conventional therapies.

It's Surprising to understand that treatment using stem cells from several sources, such as those from bone marrow and umbilical cord, was successfully used to treat numerous life threatening diseases with great results, since 1988. Over the past couple of years, with increased research and development activities, a growing number of successful stem cell treatments have emerged. It's turned into one of the most exciting area of medicine, encompassing all aspects of current medical science.

Stem Cell Therapy in India

There's Been a rapid growth of stem cell treatment in India, and is not being overambitious to feel that in India and the planet it might one day replace the expensive, painstakingly protracted and frequently ineffective conventional therapy for treating a large number of acute and chronic diseases.

We at ReeLabs are pleased to say we offer finest therapy options in accepted signs

Many clinics offering stem cell treatments make claims that are not supported by a current understanding of science {

Stem cells have enormous promise to help us understand and treat a range |} Of diseases, injuries and other health-related ailments. possible is evident in the use of blood stem cells to treat diseases of the blood, a treatment that has saved the lives of thousands of children with leukemia; also can be understood in the use of stem cells for tissue grafts to cure diseases or injury to the boneskin and surface of the eye. |} Important clinical trials involving stem cells have been penalized for a number of different ailments and researchers continue to explore new avenues using stem cells in medicine.

There's still a lot to know about stem cells, however, and their current Programs as remedies are sometimes exaggerated by the media and other parties who don't fully understand the science and current limitations, and also by"practices" looking to capitalize on the hype by promoting remedies to chronically ill or seriously injured patients. The advice on this page is intended to assist you understand the potential and the limitations of stem cells in this point in time, and also to help you spot some of the misinformation that is widely circulated by practices offering unproven remedies.

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It's important to discuss these Nine Things to Know and some other Research or information you gather with your primary care physician and other trusted members of your healthcare team in deciding what is right for you.


Stem cell researchers are making great improvements in |} Understanding normal development, figuring out exactly what goes wrong in disease and developing and testing potential treatments to assist patients. They still have much to learn, but about how stem cells work within the body and their capability for recovery. Safe and effective remedies for many diseases, ailments and injuries have been in the future. {

Stem cells: What they are and what they do |}{

Stem cells and derived
|} Products offer great promise for new medical therapies. Learn about stem cell types, current and possible applications, ethical problems, and the condition of practice and research.

You have heard about stem cells in the news, and perhaps you've wondered if They may help you or a loved one having a serious illness. You may wonder what stem cells are, how they are being used to treat injury and disease, and why they're the subject of such vigorous debate.

Here are some answers to often asked questions about stem cells.

Why is there such an interest in stem cells?

Researchers and doctors hope stem cell studies might help :

Boost understanding of how infections occur. By watching stem cells grow into cells in bones, heart muscle, nerves, and other glands and organs, researchers and physicians may better understand how diseases and ailments grow.

• Generate healthy cells to replace diseased cells (regenerative medicine). |} Stem cells can be guided into getting specific cells that can be employed to regenerate and repair diseased or damaged cells in humans.


People who might benefit from stem cell therapies |} people who have spinal cord injuries, type 1 diabetes, Parkinson's disease, Alzheimer's disease, heart disease, stroke, burns, cancer and atherosclerosis. |}

Stem cells Might Have the potential to be grown to Become new tissue for use in transplant and regenerative medicine. Researchers continue to progress the understanding on stem cells and their applications in transplant and regenerative medicine.

• Evaluation new drugs for safety and effectiveness. Before utilizing new drugs in humans, some kinds of stem cells are used to check the security and quality of investigational drugs. This type of testing will probably have an immediate impact on drug development because of prostate toxicity testing.

New areas of research comprise the effectiveness of Using human stem cells that were programmed into tissue-specific cells to check new drugs. For testing of new drugs to be true, the cells have to be programmed to obtain properties of the type of cells to be tested. Techniques to plan cells into particular cells are still to be studied.

For instance, nerve cells could be generated to Test a new drug for a neural disease. Tests could reveal whether the new drug had any effect on the cells and whether the cells had been damaged. {

What are stem cells?
|} {

Stem cells are the body's raw materials -- cells from which all other cells
|} With specialized functions are generated. Under the right conditions within the body or a lab, stem cells divide to form more cells called cells.

These daughter cells become new stem cells (self-renewal) or become Specialized cells (distinction ) using a more specific purpose, such as blood cells, brain cells, heart muscle or bone. additional cell in the body has the natural ability to generate new cell types. |} {

Where do stem cells come from?
|} {

Researchers have found several sources of stem cells: |}

• These stem cells come from embryos that are three to five days old. At this phase, an embryo is called a blastocyst and has about 150 cells.


These are pluripotent (ploo-RIP-uh-tunt) stem |} Cells, meaning that they are able to divide into more stem cells can turn into any type of cell within the body. This flexibility enables embryonic stem cells to be used to regenerate or repair diseased tissue and organs, but their use in humans is to date limited to eye-related disorders like macular degeneration.

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• Adult stem cells. These stem cells are found in tiny amounts in most adult cells, such as bone marrow or fat. In comparison with embryonic stem cells, adult stem cells have a more limited capacity to contribute to several cells of the body. |}

Until recently, researchers thought adult stem Cells could produce just similar kinds of cells. For example, researchers thought that stem cells residing in the bone marrow could contribute only to blood cells.

However, emerging evidence suggests that adult stem Cells may have the ability to create unrelated kinds of cells. For example, bone marrow stem cells may have the ability to produce bone or heart muscle cells. This research has led to early-stage clinical trials to examine usefulness and security in people. By way of example, adult stem cells are currently being tested in people with neurological or heart disease. {

Adult cells shifted to have properties of embryonic stem cells (induced pluripotent stem cells). |} Scientists have transformed regular adult cells into stem cells using genetic reprogramming. By changing the genes in the adult cells, researchers can reprogram the cells to behave similarly to embryonic stem cells.

This new technique may allow researchers to utilize These reprogrammed cells rather than embryonic stem cells and also protect against immune system rejection of their new stem cells. However, scientists don't yet understand if changing adult cells may cause adverse effects in humans.

Researchers have been able to take regular Connective tissue cells and induce them to become functional cells. In studies, animals with heart failure that were injected with new heart cells underwent improved heart function and survival time.

• Perinatal stem cells. Researchers have found stem cells in amniotic fluid along with umbilical cord blood stem cells. {These stem cells also have the capacity to change into specialized cells. |}


Amniotic fluid fills the sac that surrounds and |} Protects a growing fetus in the uterus. |} Researchers have identified stem cells in samples of amniotic fluid drawn from pregnant women through a procedure called amniocentesis, a test conducted to check for abnormalities.


More research of amniotic fluid stem cells is required |} To know their potential. {

Why is there a controversy about using embryonic stem cells?

Embryonic stem cells have been obtained from early-stage embryos -- a group of Cells that forms when a female's egg is fertilized with a person's sperm in an in vitro fertilization clinic. Since human embryonic stem cells are extracted from human embryos, several questions and issues are raised about the ethics of embryonic stem cell research. |}

The National Institutes of Health created guidelines for human stem cell Research in 2009. Guidelines included specifying embryonic stem cells and how they may be used in research and contribution guidelines for embryonic stem cells. Additionally, guidelines stated embryonic stem cells may only be used from embryos created by in vitro fertilization when the embryo is no longer needed. {

Where do these embryos come from?
|} {

The embryos Used in embryonic stem cell research come from eggs that |} Were fertilized at in vitro fertilization practices but not implanted in a woman's uterus. The stem cells have been given with informed consent from donors. The stem cells can live and grow in particular solutions in test tubes or petri dishes in labs.

Why can't investigators use adult stem cells rather? {

Although research into adult stem cells is promising, adult stem cells may |} versatile and durable as are embryonic stem cells. |} Adult stem cells may be unable to be manipulated to create all cell types, which limits how adult stem cells can be used in the treatment of diseases.

Adult stem cells also are more likely to contain abnormalities because of Environmental hazards, like radicals, or from mistakes obtained by the cells through replication. However, scientists have found that adult stem cells are more flexible than was originally suspected.

What are stem cell lines and why do researchers wish to utilize them?

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A stem cell line is a group of cells that all descend from a single original Stem cell and has been grown in a laboratory. Cells in a stem cell line keep growing but don't differentiate into specialized cells. Ideally, they remain free of genetic flaws and continue to produce more stem cells. Clusters of cells could be obtained from a stem cell line and frozen for storage or shared with other investigators.

What is stem cell treatment (regenerative medicine), and how does it function?

Stem cell treatment, also Called regenerative medicine, promotes the Reparative reaction of diseased, dysfunctional or wounded tissue using stem cells or their derivatives. It's the second chapter of organ transplantation and uses cells rather than donor organs, which can be limited in distribution.

{Researchers grow stem cells in a laboratory. |} These stem cells have been manipulated to {Specialize into particular kinds of cells, such as heart muscle cells, blood cells or neural cells. |}

The technical cells can then be implanted into someone. For example, if That the person has heart disease, the cells could be injected into the heart muscle. |} The wholesome transplanted heart cells could then contribute to fixing defective heart muscle.


Researchers have already shown that adult bone marrow cells advised to become |} Heart-like cells can repair heart tissue in people, and much more research is ongoing.

Have stem cells been used to treat diseases?

Yes, doctors have completed stem cell transplant, also Called bone marrow transplants. In stem cell transplant, stem cells replace cells damaged by disease or chemotherapy or as a way for the donor's immune system to combat some kinds of cancer and also blood-related diseases, such as leukemia. These transplants use adult stem cells or umbilical cord blood.

Researchers are examining adult stem cells to treat other ailments, Including numerous degenerative diseases like heart failure.

What are the potential difficulties with using embryonic stem cells in humans?

To be useful in humans, researchers should be certain that stem cells will needed. |}

Researchers have found ways to direct stem cells to become specific Kinds of cells, like directing embryonic stem cells to become heart cells. |} Research is ongoing in this area.

Embryonic stem cells also could grow irregularly or focus in distinct Cell types spontaneously. Researchers study how to control the growth and differentiation of embryonic stem cells.

Embryonic stem cells also might activate an immune reaction in which the Receiver's body strikes the stem cells as foreign invaders, or simply fail to function normally, with unknown impacts. Researchers continue to examine how to prevent these possible complications.

What is therapeutic cloning, and what advantages might it offer? {

Therapeutic cloning, also called somatic cell nuclear transfer, is a
|} Technique to create elastic stem cells independent of fertilized eggs. In this technique, the nucleus, which includes the genetic material, is eliminated from an unfertilized egg. The nucleus is also removed from a somatic cell of a donor. |}


This donor nucleus is then injected into the egg, replacing the nucleus that |} {Was removed, a process called nuclear transfer. |} The egg is permitted to split and soon forms a blastocyst. This procedure creates a line of stem cells that is genetically identical to the donor's -- in essence, a clone.


Some researchers Think That stem cells derived from therapeutic cloning |} May offer advantages over people from fertilized eggs since cloned cells are not as likely to be rejected once transplanted back into the donor and may allow researchers to determine exactly how a disease develops. {

Has therapeutic cloning in people been successful? |}

No. Researchers have not been able to successfully perform therapeutic Cloning with humans despite achievement in several of different species.


Nonetheless, in recent studies, researchers have created human pluripotent stem |} Cells by altering the therapeutic cloning procedure. Researchers continue to Study the potential of therapeutic cloning in people. |}